The analysis focused on immediate post-treatment symptom and cognitive changes after a course of 30-40 HBOT treatments. The review found considerable heterogeneity in the studies, but the heterogeneity strengthened the conclusions. The scientific dosage analysis found that HBOT at 1.5 ATA (1.5 times atmospheric pressure) significantly improved symptoms, cognition, and quality of life in civilians and veterans years after their TBI.

The review contained multiple studies on veterans with blast-induced traumatic brain injury and found that HBOT also significantly reduced PTSD. Those veterans with TBI and PTSD, typically the most resistant to treatment, had the greatest improvement.